APC Anti-Mouse Foxp3 (MF23)
The MF23 antibody reacts with mouse Foxp3, a 50-55 kDa transcription factor which is a central regulator of T cell activity and is critical for the development and function of regulatory T cells (Tregs). Foxp3 is a member of the forkhead box or winged helix family of transcription factors and is expressed at constitutively high levels in Treg cells. Forced expression of Foxp3 in conventional T cells results in the upregulation of Treg associated molecules such as CD25, CTLA-4, and GITR and is sufficient to impart suppressive functional activity to these cells.
| Name | APC Anti-Mouse Foxp3 (MF23) |
|---|---|
| Cat. No. | 20-0191 |
| Alternative Names | Forkhead box P3, Scurfin, JM2 |
| Gene ID | 20371 |
| Clone | MF23 |
| Isotype | Rat IgG2b |
| Reactivity | Mouse |
| Format | APC |
| Application | Flow Cytometry |
Original: $119.00
-70%$119.00
$35.70
Description
The MF23 antibody reacts with mouse Foxp3, a 50-55 kDa transcription factor which is a central regulator of T cell activity and is critical for the development and function of regulatory T cells (Tregs). Foxp3 is a member of the forkhead box or winged helix family of transcription factors and is expressed at constitutively high levels in Treg cells. Forced expression of Foxp3 in conventional T cells results in the upregulation of Treg associated molecules such as CD25, CTLA-4, and GITR and is sufficient to impart suppressive functional activity to these cells.
| Name | APC Anti-Mouse Foxp3 (MF23) |
|---|---|
| Cat. No. | 20-0191 |
| Alternative Names | Forkhead box P3, Scurfin, JM2 |
| Gene ID | 20371 |
| Clone | MF23 |
| Isotype | Rat IgG2b |
| Reactivity | Mouse |
| Format | APC |
| Application | Flow Cytometry |
