APC/Cyanine7 anti-human VISTA (PD-1H)
VISTA (V-domain Ig suppressor of T cell activation), also known as PD-1H, is a type I transmembrane protein with a single extracellular IgV domain. VISTA is expressed by a subset of T cells, macrophages, dendritic cells, neutrophils, and NK cells. It was reported that in certain tumor environment, there is low-pH dependent interaction between VISTA and PSGL1. However, the physiological binding partner for VISTA and the mechanism of its action are not clearly understood. VISTA is considered as a checkpoint regulator and a promising target for cancer immunotherapy.
PRODUCT DETAILS
Clone: A17002B
Antibody Type: Monoclonal
Reactivity: Human
Format: VISTA
Host: Mouse
Isotype: IgG2b, κ
Applications: FC - Quality tested
Regulatory Status: RUO
Note to Purchaser: This product is manufactured and supplied by BioLegend, Inc. under an agreement between BioLegend, Inc. and Cytek Biosciences, Inc. Information related to this product is provided by BioLegend, Inc.
Description
VISTA (V-domain Ig suppressor of T cell activation), also known as PD-1H, is a type I transmembrane protein with a single extracellular IgV domain. VISTA is expressed by a subset of T cells, macrophages, dendritic cells, neutrophils, and NK cells. It was reported that in certain tumor environment, there is low-pH dependent interaction between VISTA and PSGL1. However, the physiological binding partner for VISTA and the mechanism of its action are not clearly understood. VISTA is considered as a checkpoint regulator and a promising target for cancer immunotherapy.
PRODUCT DETAILS
Clone: A17002B
Antibody Type: Monoclonal
Reactivity: Human
Format: VISTA
Host: Mouse
Isotype: IgG2b, κ
Applications: FC - Quality tested
Regulatory Status: RUO
Note to Purchaser: This product is manufactured and supplied by BioLegend, Inc. under an agreement between BioLegend, Inc. and Cytek Biosciences, Inc. Information related to this product is provided by BioLegend, Inc.
