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PE Anti-Mouse CD11a (M17/4)

PE Anti-Mouse CD11a (M17/4)

TDS | SDS

The M17/4 monoclonal antibody reacts with mouse CD11a, an 180kD glycoprotein that is also known as integrin alpha L (ITGAL). CD11a associates non-covalently with CD18 (integrein beta 2) to form the lymphocyte function associated antigen-1 (LFA-1) heterodimer. CD11a is expressed on the cell surface of all leukocytes. LFA-1 plays a critical role in intercellular adhesion that is mediated through interactions with its ligands, ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50). LFA-1 also functions in lymphocyte costimulatory signaling. On resting cells, LFA-1 exists in a low-affinity conformation that is rapidly induced to the high-affinity conformation following cell stimulation.

Name PE Anti-Mouse CD11a (M17/4)
Cat. No. 50-0111
Alternative Names alpha L integrin α. CD11 antigen-like family member A. integrin αalpha-L. leukocyte adhesion glycoprotein LFA-1 alpha chain. leukocyte function-associated molecule 1 alpha chain. lymphocyte antigen 15. lymphocyte function associated antigen 1, alpha polypeptide
Gene ID 16408
Clone M17/4
Isotype Rat IgG2a, kappa
Reactivity Mouse
Format PE
Application Flow Cytometry
Select Size
From $15.60

Original: $52.00

-70%
PE Anti-Mouse CD11a (M17/4)—

$52.00

$15.60
Product image 1

Description

TDS | SDS

The M17/4 monoclonal antibody reacts with mouse CD11a, an 180kD glycoprotein that is also known as integrin alpha L (ITGAL). CD11a associates non-covalently with CD18 (integrein beta 2) to form the lymphocyte function associated antigen-1 (LFA-1) heterodimer. CD11a is expressed on the cell surface of all leukocytes. LFA-1 plays a critical role in intercellular adhesion that is mediated through interactions with its ligands, ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50). LFA-1 also functions in lymphocyte costimulatory signaling. On resting cells, LFA-1 exists in a low-affinity conformation that is rapidly induced to the high-affinity conformation following cell stimulation.

Name PE Anti-Mouse CD11a (M17/4)
Cat. No. 50-0111
Alternative Names alpha L integrin α. CD11 antigen-like family member A. integrin αalpha-L. leukocyte adhesion glycoprotein LFA-1 alpha chain. leukocyte function-associated molecule 1 alpha chain. lymphocyte antigen 15. lymphocyte function associated antigen 1, alpha polypeptide
Gene ID 16408
Clone M17/4
Isotype Rat IgG2a, kappa
Reactivity Mouse
Format PE
Application Flow Cytometry
PE Anti-Mouse CD11a (M17/4) | Cytek Biosciences