violetFluor™ 450 Anti-Mouse CD45.1 (A20)
The A20 antibody reacts with mouse CD45.1, also known as Ly5.1, which is a strain-specific allelic form of the CD45 Leukocyte Common Antigen (LCA). Functionally, CD45 is a protein tyrosine phosphatase whose broad cell distribution supports a critical role in many leukocyte functions, including regulation of signal transduction and cell activation associated with the T cell and B cell receptors.
The A20 antibody is typically used as a leukocyte marker in Ly5.1 mouse strains: SJL/J, DA, STS/A and RIII. The antibody has been demonstrated to specific for CD45.1 and is not cross-reactive with CD45.2 bearing cells.
Recent Publications:
Lin CC, Bradstreet TR, Schwarzkopf EA, Jarjour NN, Chou C, Archambault AS, Sim J, Zinselmeyer BH, Carrero JA, Wu GF, Taneja R, Artyomov MN, Russell JH and Edelson BT. 2016. J Exp Med. 213(2): 251-271. (Flow Cytometry)
| Name | violetFluor™ 450 Anti-Mouse CD45.1 (A20) |
|---|---|
| Cat. No. | 75-0453 |
| Alternative Names | SJL, Ly5.1 |
| Gene ID | 19264 |
| Clone | A20 |
| Isotype | Mouse IgG2a, κ |
| Reactivity | Mouse |
| Format | violetFluor™ 450 |
| Application | Flow Cytometry |
Description
The A20 antibody reacts with mouse CD45.1, also known as Ly5.1, which is a strain-specific allelic form of the CD45 Leukocyte Common Antigen (LCA). Functionally, CD45 is a protein tyrosine phosphatase whose broad cell distribution supports a critical role in many leukocyte functions, including regulation of signal transduction and cell activation associated with the T cell and B cell receptors.
The A20 antibody is typically used as a leukocyte marker in Ly5.1 mouse strains: SJL/J, DA, STS/A and RIII. The antibody has been demonstrated to specific for CD45.1 and is not cross-reactive with CD45.2 bearing cells.
Recent Publications:
Lin CC, Bradstreet TR, Schwarzkopf EA, Jarjour NN, Chou C, Archambault AS, Sim J, Zinselmeyer BH, Carrero JA, Wu GF, Taneja R, Artyomov MN, Russell JH and Edelson BT. 2016. J Exp Med. 213(2): 251-271. (Flow Cytometry)
| Name | violetFluor™ 450 Anti-Mouse CD45.1 (A20) |
|---|---|
| Cat. No. | 75-0453 |
| Alternative Names | SJL, Ly5.1 |
| Gene ID | 19264 |
| Clone | A20 |
| Isotype | Mouse IgG2a, κ |
| Reactivity | Mouse |
| Format | violetFluor™ 450 |
| Application | Flow Cytometry |
